Author: M. Elizabeth Halloran
Edition: 2010
Publisher: Springer
Binding: Hardcover
ISBN: 0387403132
Design and Analysis of Vaccine Studies (Statistics for Biology and Health)
Widespread immunization has many different kinds of effects in individuals and populations, including in the unvaccinated individuals. Medical books Design and Analysis of Vaccine Studies . The challenge is in understanding and estimating all of these effects. This book presents a unified conceptual framework of the different effects of vaccination at the individual and at the population level. The book covers many different vaccine effects, including vaccine efficacy for susceptibility, for disease, for post-infection outcomes, and for infectiousness. The book includes methods for evaluating indirect, total and overall effects of vaccination programs in populations Medical books Design and Analysis of Vaccine Studies. Design and Analysis of Vaccine Studies
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Design and Analysis of Vaccine Studies
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author claudio jose struchiner author ira m longini author m elizabeth halloran format hardback language english publication year 15 12 2009 series statistics for biology and health subject medicine subject 2 clinical medicine professional title design and analysis of vaccine studies author halloran m elizabeth longini ira m jr struchiner claudio jose publisher springer verlag publication date jan 01 2010 pages 404 binding hardcover edition 1 st dimensions 6 25 wx 9 25 hx 1 00 d isbn 038740313
As well as being a reference for the design, analysis, and interpretation of vaccine studies, the text covers all design and analysis stages, from vaccine development to post-licensure surveillance, presenting likelihood, frequentists, and Bayesian approaches.
Medical Book Design and Analysis of Vaccine Studies
The challenge is in understanding and estimating all of these effects. This book presents a unified conceptual framework of the different effects of vaccination at the individual and at the population level. The book covers many different vaccine effects, including vaccine efficacy for susceptibility, for disease, for post-infection outcomes, and for infectiousness. The book includes methods for evaluating indirect, total and overall effects of vaccination programs in populations. Topics include household studies, evaluating correlates of immune protection, and applications of casual inference. Material on concepts of infectious disease epidemiology, transmission models, casual inference, and vaccines provides background for the reader. This is the first book to present vaccine evaluation in this comprehensive conceptual framework. This book is intended for colleagues and students in statistics, biostatistics, epidemiology, and infectious diseases. Most essential concepts are described in simple language accessible to epidemiologists, followed by technical material accessible to statisticians.