Saturday, January 15, 2011

Chemistry and Molecular Aspects of Drug Design and Action

Chemistry and Molecular Aspects of Drug Design and Action



Author:
Edition: 1
Publisher: CRC Press
Binding: Hardcover
ISBN: 0849390060



Chemistry and Molecular Aspects of Drug Design and Action


An ever-increasing demand for better drugs, elevated safety standards, and economic considerations have all led to a dramatic paradigm shift in the way that drugs are being discovered and developed. Medical books Chemistry and Molecular Aspects of Drug Design and Action. Known as rational drug design, this contemporary process is defined by three main steps: the discovery of lead compounds, surgical manipulation to develop pharmacophores, and further optimization to produce the best compounds.

Chemistry and Molecular Aspects of Drug Design and Action brings together an impressive collection of world-renowned pharmacochemistry scientists who are currently defining the emergence of rational drug design. Offering insight from their own specialized research, these pioneers highlight the variety of approaches being employed in this field, including those that start by considering either molecular mechanisms of drug action, or the metabolizing enzyme action occurring in the structure of a drug molecule. Another approach they explore is one that starts from the pathobiochemistry and pathophysiology of target diseases Medical books Chemistry And Molecular Aspects Of Drug Design And Action Rekka, E. A. (edited B. format hardback language english publication year 28 04 2008 subject engineering technology subject 2 industrial chemistry manufacturing title chemistry and molecular aspects of drug design and action author rekka ea edited by kourounakis pn edited by publisher crc pr i llc publication date apr 24 2008 pages 356 binding hardcover edition 1 st dimensions 6 25 wx 9 25 hx 1 00 d isbn 0849390060 subject science chemistry general description this work brings together pharmacochemistry researchers

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format hardback language english publication year 28 04 2008 subject engineering technology subject 2 industrial chemistry manufacturing title chemistry and molecular aspects of drug design and action author rekka ea edited by kourounakis pn edited by publisher crc pr i llc publication date apr 24 2008 pages 356 binding hardcover edition 1 st dimensions 6 25 wx 9 25 hx 1 00 d isbn 0849390060 subject science chemistry general description this work brings together pharmacochemistry researchers

Store Search search Title, ISBN and Author Chemistry and Molecular Aspects of Drug Design and Action by PN Kourounakis, EA Rekka Estimated delivery 3-12 business days Format Hardcover Condition Brand New Drawing from synthetic chemistry, molecular modeling, computational biology, structural genomics, and pharmacology, this book explores medicinal chemistry. It focuses on the correlation of properties and biological activity, and delves into the phenomenon of xenobiotic metabolism. Publisher

"An ever-increasing demand for better drugs, elevated safety standards, and economic considerations have all led to a dramatic paradigm shift in the way that drugs are being discovered and developed. Known as rational drug design, this contemporary process is defined by three main steps: the discovery of lead compounds, surgical manipulation to develop pharmacophores, and further optimization to produce the best compounds. Chemistry and Molecular Aspects of Drug Design and Action brings together an impressive collection of world-renowned pharmacochemistry scientists who are currently defining

"An ever-increasing demand for better drugs, elevated safety standards, and economic considerations have all led to a dramatic paradigm shift in the way that drugs are being discovered and developed. Known as rational drug design, this contemporary process is defined by three main steps: the discovery of lead compounds, surgical manipulation to develop pharmacophores, and further optimization to produce the best compounds. Chemistry and Molecular Aspects of Drug Design and Action brings together an impressive collection of world-renowned pharmacochemistry scientists who are currently defining



Medical Book Chemistry and Molecular Aspects of Drug Design and Action



Known as rational drug design, this contemporary process is defined by three main steps: the discovery of lead compounds, surgical manipulation to develop pharmacophores, and further optimization to produce the best compounds.

Chemistry and Molecular Aspects of Drug Design and Action brings together an impressive collection of world-renowned pharmacochemistry scientists who are currently defining the emergence of rational drug design. Offering insight from their own specialized research, these pioneers highlight the variety of approaches being employed in this field, including those that start by considering either molecular mechanisms of drug action, or the metabolizing enzyme action occurring in the structure of a drug molecule. Another approach they explore is one that starts from the pathobiochemistry and pathophysiology of target diseases. Furthermore, the book also considers drug development that makes use of already developed compounds stored in data banks.

Divided into five parts, each dedicated to various aspects of the classical medicinal chemistry approach, the text makes it easy for readers to focus on a field of specific interest.

  • Chemical, Biochemical, and Biological Aspects of Pathophysiological Conditions
  • Classical Medicinal Chemistry
  • Drug Design, Chemical and Molecular Aspects of Drug Action
  • Drug Xenobiotic Metabolism
  • Physical Organic and Theoretical Medicinal Chemistry
  • While each section can be studied independently, the combined material in this volume provides the most comprehensive overview available on rational drug design. This work is an invaluable resource both for those entering the field, as well as those researchers looking to build on current progress.

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