Thursday, February 17, 2011

Hot-Melt Extrusion pdf

Hot-Melt Extrusion



Author: Dennis Douroumis
Edition: 1
Publisher: Wiley
Binding: Hardcover
ISBN: 0470711183



Hot-Melt Extrusion: Pharmaceutical Applications (Advances in Pharmaceutical Technology)


Hot-melt extrusion (HME)  - melting a substance and forcing it through an orifice under controlled conditions to form a new material - is an emerging processing technology in the pharmaceutical industry for the preparation of various dosage forms and drug delivery systems, for example granules and sustained release tablets. Medical books Hot-Melt Extrusion. p>Hot-Melt Extrusion: Pharmaceutical Applications covers the main instrumentation, operation principles and theoretical background of HME. It then focuses on HME drug delivery systems, dosage forms and clinical studies (including pharmacokinetics and bioavailability) of HME products. Finally, the book includes some recent and novel HME applications, scale -up considerations and regulatory issues. Topics covered include:

  • principles and die design of single screw extrusion
  • twin screw extrusion techniques and practices in the laboratory and on production scale
  • HME developments for the pharmaceutical industry
  • solubility parameters for prediction of drug/polymer miscibility in HME formulations
  • the influence of plasticizers in HME
  • applications of polymethacrylate polymers in HME
  • HME of ethylcellulose, hypromellose, and polyethylene oxide
  • bioadhesion properties of polymeric films produced by HME
  • taste masking using HME
  • clinical studies, bioavailability and pharmacokinetics of HME products
  • injection moulding and HME processing for pharmaceutical materials
  • laminar dispersive & distributive mixing with dissolution and applications to HME
  • technological considerations related to scale-up of HME processes
  • devices and implant systems by HME
  • an FDA perspective on HME product and process understanding
  • improved process understanding and control of an HME process with near-infrared spectroscopy

Hot-Melt Extrusion: Pharmaceutical Applications is an essential multidisciplinary guide to the emerging pharmaceutical uses of this processing technology for researchers in academia and industry working in drug formulation and delivery, pharmaceutical engineering and processing, and polymers and materials science Medical books Hot-melt Extrusion By Dionysios Douroumis. Store Search search Title, ISBN and Author Hot-Melt Extrusion by Dennis Douroumis Estimated delivery 3-12 business days Format Hardcover Condition Brand New Hot-melt extrusion (HME) - melting a substance and forcing it through an orifice under controlled conditions to form a new material - is an emerging processing technology in the pharmaceutical industry for the preparation of various dosage forms and drug delivery systems, for example granules and sustained release tablets. Publisher Descrip

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Download link for CRL Hot Melt Extruder Gun by CR Laurence

Store Search search Title, ISBN and Author Hot-Melt Extrusion by Dennis Douroumis Estimated delivery 3-12 business days Format Hardcover Condition Brand New Hot-melt extrusion (HME) - melting a substance and forcing it through an orifice under controlled conditions to form a new material - is an emerging processing technology in the pharmaceutical industry for the preparation of various dosage forms and drug delivery systems, for example granules and sustained release tablets. Publisher Descrip

"First book related to the use of hot melt extrusion for pharmaceutical applications"--

Pam-Buehnen Glue Gun, Hot Melt, 600 Watt, 12 1/4 In. HB 700KD Extrusion Glue Gun Hot Glue GunsGlue Gun, Hot Melt, Size 10

Hot-melt extrusion (HME) - melting a substance and forcing it through an orifice under controlled conditions to form a new material - is an emerging processing technology in the pharmaceutical industry for the preparation of various dosage forms and drug delivery systems, for example granules and sustained release tablets."Hot-Melt Extrusion: Pharmaceutical Applications" covers the main instrumentation, operation principles and theoretical background of HME. It then focuses on HME drug delivery systems, dosage forms and clinical studies (including pharmacokinetics and bioavailability) of HME p



Medical Book Hot-Melt Extrusion



p>Hot-Melt Extrusion: Pharmaceutical Applications covers the main instrumentation, operation principles and theoretical background of HME. It then focuses on HME drug delivery systems, dosage forms and clinical studies (including pharmacokinetics and bioavailability) of HME products. Finally, the book includes some recent and novel HME applications, scale -up considerations and regulatory issues. Topics covered include:

  • principles and die design of single screw extrusion
  • twin screw extrusion techniques and practices in the laboratory and on production scale
  • HME developments for the pharmaceutical industry
  • solubility parameters for prediction of drug/polymer miscibility in HME formulations
  • the influence of plasticizers in HME
  • applications of polymethacrylate polymers in HME
  • HME of ethylcellulose, hypromellose, and polyethylene oxide
  • bioadhesion properties of polymeric films produced by HME
  • taste masking using HME
  • clinical studies, bioavailability and pharmacokinetics of HME products
  • injection moulding and HME processing for pharmaceutical materials
  • laminar dispersive & distributive mixing with dissolution and applications to HME
  • technological considerations related to scale-up of HME processes
  • devices and implant systems by HME
  • an FDA perspective on HME product and process understanding
  • improved process understanding and control of an HME process with near-infrared spectroscopy

Hot-Melt Extrusion: Pharmaceutical Applications is an essential multidisciplinary guide to the emerging pharmaceutical uses of this processing technology for researchers in academia and industry working in drug formulation and delivery, pharmaceutical engineering and processing, and polymers and materials science.

This is the first book from our brand new series Advances in Pharmaceutical Technology. Find out more about the series here.



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