Development Safety Update Report (DSUR) Harmonizing the Format and Content for Periodic Safety Report during Clinical Trials

Author: CIOMS
Edition: 1
Publisher: World Health Organization
Binding: Paperback
ISBN: 9290360801

Development Safety Update Report (DSUR) Harmonizing the Format and Content for Periodic Safety Report during Clinical Trials: Report of CIOMS Working Group VII (A CIOMS Publication)

Regular and timely review appraisal and communication of safety information are critical to risk management during the clinical development of drugs. Medical books Development Safety Update Report (DSUR) Harmonizing the Format and Content for Periodic Safety Report during Clinical Trials. Whereas the overall goal of a clinical development program is to characterize the benefit-risk relationship of the product in a particular patient population, the risk to individual trial subjects is a critical consideration during product development at a time when the effectiveness of a product is generally uncertain. By conducting an overall appraisal of safety data at regular intervals, risks can be recognized thoughtfully assessed and appropriately communicated to all interested stakeholders to support the safety of clinical trial subjects.

Although regulatory authorities currently require the submission of a periodic safety report during the conduct of clinical trials, there are substantial differences in the format content and timing of the different reports. The CIOMS VII Working group is proposing in this new publication an internationally harmonized document namely the Development Safety Update Report (DSUR) that is modeled after the Periodic Safety Update Report (PSUR) for marketed products Medical books Development Safety Update Report (DSUR), Harmonizing the Format and Content for Periodic Safety During Clinical Trials By Council for International Organizations of Medical Sciences (COR). *Author: Council for International Organizations of Medical Sciences (COR) *Series Title: Report of Cioms Working Group *Publication Date: 2006/12/01 *Number of Pages: 203 *Binding Type: Paperback *Language: English *Depth: 0.25 *Width: 6.25 *Height: 9.50

Download link for Development Safety Update Report (DSUR), Harmonizing the Format and Content for Periodic Safety During Clinical T... (Paperback)

*Author: Council for International Organizations of Medical Sciences (COR) *Series Title: Report of Cioms Working Group *Publication Date: 2006/12/01 *Number of Pages: 203 *Binding Type: Paperback *Language: English *Depth: 0.25 *Width: 6.25 *Height: 9.50

author cioms author unaids author who author who world health organization unaids author world health organization format paperback language english publication year 17 12 2006 subject medicine subject 2 medical nursing ancillary services title the development safety update report dsur harmonizing the format and content for periodic safety reporting during clinical trials report of cioms working group vii report of cioms working group vii author cioms working group on the development safety upda

Powered by Frooition Pro Click here to view full size. Full Size Image Click to close full size. Development Safety Update Report (DSUR), Harmonizing the Format and Content for Periodic Safety During Clinical Trials - Book NEW Author(s): Council for International Organizations of Medical Sciences Format: Paperback # Pages: 203 ISBN-13: 9789290360803 Published: 12/01/2006 Language: English Weight: 0.90 pounds Brand new book. About Us Payment Shipping Customer Service FAQs Welcome to MovieMars Al

Medical Book Development Safety Update Report (DSUR) Harmonizing the Format and Content for Periodic Safety Report during Clinical Trials

Whereas the overall goal of a clinical development program is to characterize the benefit-risk relationship of the product in a particular patient population, the risk to individual trial subjects is a critical consideration during product development at a time when the effectiveness of a product is generally uncertain. By conducting an overall appraisal of safety data at regular intervals, risks can be recognized thoughtfully assessed and appropriately communicated to all interested stakeholders to support the safety of clinical trial subjects.

Although regulatory authorities currently require the submission of a periodic safety report during the conduct of clinical trials, there are substantial differences in the format content and timing of the different reports. The CIOMS VII Working group is proposing in this new publication an internationally harmonized document namely the Development Safety Update Report (DSUR) that is modeled after the Periodic Safety Update Report (PSUR) for marketed products. It presents the general principles behind the preparation and use of the DSUR and a model DSUR. The model is illustrated with sample fictitious DSURs for a commercial and non-commercial (trial-specific) sponsor.

An Introduction to Statistics in Early Phase Trials Epub

Author: Steven Julious
Edition: 1
Publisher: Wiley
Binding: Hardcover
ISBN: 0470059850

An Introduction to Statistics in Early Phase Trials

All new medicines and devices undergo early phase trials to assess, interpret and better understand their efficacy, tolerability and safety. Medical books An Introduction to Statistics in Early Phase Trials. An Introduction to Statistics in Early Phase Trials describes the practical design and analysis of these important early phase clinical trials and provides the crucial statistical basis for their interpretation. It clearly and concisely provides an overview of the most common types of trials undertaken in early phase clinical research and explains the different methodologies used. The impact of statistical technologies on clinical development and the statistical and methodological basis for making clinical and investment decisions are also explained.

• Conveys key ideas in a concise manner understandable by non-statisticians
• Explains how to optimise designs in a constrained or fixed resource setting
• Discusses decision making criteria at the end of Phase II trials
• Highlights practical day-to-day issues and reporting of early phase trials

An Introduction to Statistics in Early Phase Trials is an essential guide for all researchers working in early phase clinical trial development, from clinical pharmacologists and pharmacokineticists through to clinical investigators and medical statisticians Medical books An Introduction to Statistics in Early Phase Trials, 9780470059852. An Introduction to Statistics in Early Phase Trials, ISBN-13: 9780470059852, ISBN-10: 0470059850

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An Introduction to Statistics in Early Phase Trials, ISBN-13: 9780470059852, ISBN-10: 0470059850

Presents an overview of the some of the most common types of trial undertaken in early clinical development. This title describes how information at the end of early phase development can be brought together to facilitate and enhance decisions pertinent to a clinical development programme.

Categories: Biometry->Methods, Drugs->Testing->Statistical methods. Contributors: Steven Julious - Author. Format: Hardcover

Categories: Biometry->Methods, Drugs->Testing->Statistical methods. Contributors: Steven Julious - Author. Format: Hardcover

Medical Book An Introduction to Statistics in Early Phase Trials

An Introduction to Statistics in Early Phase Trials describes the practical design and analysis of these important early phase clinical trials and provides the crucial statistical basis for their interpretation. It clearly and concisely provides an overview of the most common types of trials undertaken in early phase clinical research and explains the different methodologies used. The impact of statistical technologies on clinical development and the statistical and methodological basis for making clinical and investment decisions are also explained.

• Conveys key ideas in a concise manner understandable by non-statisticians
• Explains how to optimise designs in a constrained or fixed resource setting
• Discusses decision making criteria at the end of Phase II trials
• Highlights practical day-to-day issues and reporting of early phase trials

An Introduction to Statistics in Early Phase Trials is an essential guide for all researchers working in early phase clinical trial development, from clinical pharmacologists and pharmacokineticists through to clinical investigators and medical statisticians. It is also a valuable reference for teachers and students of pharmaceutical medicine learning about the design and analysis of clinical trials.

Analysis of Clinical Trials Using SAS pdf

Author: Alex Dmitrienko
Edition: 1
Publisher: SAS Institute
Binding: Paperback
ISBN: 1590475046

Analysis of Clinical Trials Using SAS: A Practical Guide

This comprehensive guide bridges the gap between modern statistical methodology and real-world clinical trial applications. Medical books Analysis of Clinical Trials Using SAS. Step-by-step instructions illustrated with examples from actual trials and case studies serve to define a statistical method and its relevance in a clinical trials setting and to illustrate how to implement the method rapidly and efficiently using the power of SAS software. Topics reflect the International Conference on Harmonization (ICH) guidelines for the pharmaceutical industry and address important statistical problems encountered in clinical trials, including analysis of stratified data, incomplete data, multiple inferences, issues arising in safety and efficacy monitoring, and reference intervals for extreme safety and diagnostic measurements. Clinical statisticians, research scientists, and graduate students in biostatistics will greatly benefit from the decades of clinical research experience compiled in this book. Numerous ready-to-use SAS macros and example code are included Medical books Analysis Of Clinical Trials Using Sas: A Practical Guid. Store Search search Title, ISBN and Author Analysis of Clinical Trials Using SAS: A Practical Guide by Alex PH.D. Dmitrienko, Walter Offen Estimated delivery 3-12 business days Format Paperback Condition Brand New Concentrating on the most important problems arising in the context of clinical trials and medical research in general, this book discusses solutions to these problems based on modern statistical methods and reviews SAS techniques that help clinical researchers efficiently and rapidly

Download link for Analysis Of Clinical Trials Using Sas Analysis Of Cl..., 9781590475041

Store Search search Title, ISBN and Author Analysis of Clinical Trials Using SAS: A Practical Guide by Alex PH.D. Dmitrienko, Walter Offen Estimated delivery 3-12 business days Format Paperback Condition Brand New Concentrating on the most important problems arising in the context of clinical trials and medical research in general, this book discusses solutions to these problems based on modern statistical methods and reviews SAS techniques that help clinical researchers efficiently and rapidly

TheNile.com.au About FAQ Payment Delivery Contact Us 1800-987-323 Analysis of Clinical Trials Using SAS: A Practical Guide (English) by Alex PH.D. Dmitrienko , Walter Offen Format Paperback Condition Brand New Language English Concentrating on the most important problems arising in the context of clinical trials and medical research in general, this book discusses solutions to these problems based on modern statistical methods and reviews SAS techniques that help clinical researchers efficientl

This comprehensive guide bridges the gap between modern statistical methodology and real-world clinical trial applications. Step-by-step instructions illustrated with examples from actual trials and case studies serve to define a statistical method and its relevance in a clinical trials setting and to illustrate how to implement the method rapidly and efficiently using the power of SAS software. Topics reflect the International Conference on Harmonization (ICH) guidelines for the pharmaceutical industry and address important statistical problems encountered in clinical trials, including analys

Concentrating on the most important problems arising in the context of clinical trials and medical research in general, this book discusses solutions to these problems based on modern statistical methods and reviews SAS techniques that help clinical researchers efficiently and rapidly implement these methods. The choice of topics reflects the International Conference on Harmonization (ICH) guidelines for the pharmaceutical industry.

Medical Book Analysis of Clinical Trials Using SAS

Step-by-step instructions illustrated with examples from actual trials and case studies serve to define a statistical method and its relevance in a clinical trials setting and to illustrate how to implement the method rapidly and efficiently using the power of SAS software. Topics reflect the International Conference on Harmonization (ICH) guidelines for the pharmaceutical industry and address important statistical problems encountered in clinical trials, including analysis of stratified data, incomplete data, multiple inferences, issues arising in safety and efficacy monitoring, and reference intervals for extreme safety and diagnostic measurements. Clinical statisticians, research scientists, and graduate students in biostatistics will greatly benefit from the decades of clinical research experience compiled in this book. Numerous ready-to-use SAS macros and example code are included.

Design and Analysis of Cluster Randomization Trials in Health Research

Author: Allan Donner
Edition: 1
Publisher: Wiley
Binding: Hardcover
ISBN: 0340691530

Design and Analysis of Cluster Randomization Trials in Health Research (Hodder Arnold Publication)

A cluster randomization trial is one in which intact social units, or clusters of individuals, are randomized to different intervention groups. Medical books Design and Analysis of Cluster Randomization Trials in Health Research . Medical books Design and Analysis of Cluster Randomization Trials in Health Research.

Download link for Design And Analysis Of Cluster Randomization Trials In Health Research Donner

Hardcover book, 464 pages. Published by John Wiley & Sons (2000)

Contributors: Allan Donner - Author. Format: Hardcover

Contributors: Allan Donner - Author. Format: Hardcover

Medical Book Design and Analysis of Cluster Randomization Trials in Health Research

Trials randomizing clusters have become particularly widespread in the evaluation of non-therapeutic interventions, including lifestyle modification, educational programmes and innovations in the provision of health care. The increasing popularity of this design among health researchers over the past two decades has led to an extensive body of methodology on the subject. This is the first book to present a systematic and united treatment of this topic; it contains distinctive chapters on the history of cluster randomized trials, ethical issues and reporting guidelines.

A Practical Guide to Cluster Randomised Trials in Health Services Research Epub

Author: Sandra Eldridge
Edition: 1
Publisher: Wiley
Binding: Kindle Edition
ISBN: B006XNJALS

A Practical Guide to Cluster Randomised Trials in Health Services Research (Statistics in Practice)

Cluster randomisedtrials are trials in which groups (or clusters) of individuals are randomly allocated to different forms of treatment. Medical books A Practical Guide to Cluster Randomised Trials in Health Services Research . In health care, these trials often compare different ways of managing a disease or promoting healthy living, in contrast to conventional randomised trials which randomise individuals to different treatments, classically comparing new drugs with a placebo. They are increasingly common in health services research. This book addresses the statistical, practical, and ethical issues arising from allocating groups of individuals, or clusters, to different interventions.

 Key features: 

• Guides readers through the stages of conducting a trial, from recruitment to reporting Medical books A Practical Guide to Cluster Randomised Trials in Health Services Research (Statistics in Practice). "Cluster randomisedtrials are trials in which groups (or clusters) of individuals are randomly allocated to different forms of treatment. In health care, these trials often compare different ways of managing a disease or promoting healthy living, in contrast to conventional randomised trials which randomise individuals to different treatments, classically comparing new drugs with a placebo. They are increasingly common in health services research. This book addresses the statistical, practical, and ethical issues arising from allocating groups of individuals, or clusters, to different interventions. Key features: Guides readers through the stages of conducting a trial, from recruitment to reporting.Presents a wide range of examples with particular emphasis on trials in health services research and primary care, with both principles and techniques explained.Topics are specifically presented in the order in which investigators think about issues when they are designing a trial.Combines information on the latest developments in the field together with a practical guide to the design and implementation of cluster randomised trials.Explains principles and techniques through numerous examples including many from the authors own experience.Includes a wide range of references for those who wish to read further. This book is intended as a practical guide, written for researchers from the health professions including doctors, psychologists, and allied health professionals, as well as statisticians involved in the design, execution, analysis and reporting of cluster randomised trials. Those with a more general interest will find the plentiful examples illuminating. File Size: 2279 KBPrint Length: 298 pagesPublisher: Wiley; 1 edition (January 9, 2012) Sold by: Amazon Digital Services, Inc.Language: EnglishASIN: B006XNJALS"
  
  

  Download link for A Practical Guide To Cluster Randomised Trials In Health Services Research (Statistics In Practice)

  
  "Cluster randomisedtrials are trials in which groups (or clusters) of individuals are randomly allocated to different forms of treatment. In health care, these trials often compare different ways of managing a disease or promoting healthy living, in contrast to conventional randomised trials which randomise individuals to different treatments, classically comparing new drugs with a placebo. They are increasingly common in health services research. This book addresses the statistical, practical, and ethical issues arising from allocating groups of individuals, or clusters, to different interven
  
  
  
  "Cluster randomisedtrials are trials in which groups (or clusters) of individuals are randomly allocated to different forms of treatment. In health care, these trials often compare different ways of managing a disease or promoting healthy living, in contrast to conventional randomised trials which randomise individuals to different treatments, classically comparing new drugs with a placebo. They are increasingly common in health services research. This book addresses the statistical, practical, and ethical issues arising from allocating groups of individuals, or clusters, to different interven
  
  
  
  "Cluster randomisedtrials are trials in which groups (or clusters) of individuals are randomly allocated to different forms of treatment. In health care, these trials often compare different ways of managing a disease or promoting healthy living, in contrast to conventional randomised trials which randomise individuals to different treatments, classically comparing new drugs with a placebo. They are increasingly common in health services research. This book addresses the statistical, practical, and ethical issues arising from allocating groups of individuals, or clusters, to different interven
  
  
  
  "Cluster randomisedtrials are trials in which groups (or clusters) of individuals are randomly allocated to different forms of treatment. In health care, these trials often compare different ways of managing a disease or promoting healthy living, in contrast to conventional randomised trials which randomise individuals to different treatments, classically comparing new drugs with a placebo. They are increasingly common in health services research. This book addresses the statistical, practical, and ethical issues arising from allocating groups of individuals, or clusters, to different interven
  
  
  
  
  

  Medical Book A Practical Guide to Cluster Randomised Trials in Health Services Research

  
  
  In health care, these trials often compare different ways of managing a disease or promoting healthy living, in contrast to conventional randomised trials which randomise individuals to different treatments, classically comparing new drugs with a placebo. They are increasingly common in health services research. This book addresses the statistical, practical, and ethical issues arising from allocating groups of individuals, or clusters, to different interventions.

   Key features: 

  • Guides readers through the stages of conducting a trial, from recruitment to reporting.
  • Presents a wide range of examples with particular emphasis on trials in health services research and primary care, with both principles and techniques explained.
  • Topics are specifically presented in the order in which investigators think about issues when they are designing a trial.
  • Combines information on the latest developments in the field together with a practical guide to the design and implementation of cluster randomised trials.
  • Explains principles and techniques through numerous examples including many from the authors own experience.
  • Includes a wide range of references for those who wish to read further. 

  This book is intended as a practical guide, written for researchers from the health professions including doctors, psychologists, and allied health professionals, as well as statisticians involved in the design, execution, analysis and reporting of cluster randomised trials. Those with a more general interest will find the plentiful examples illuminating.

   
  
  

Textbook of Clinical Trials

Author:
Edition:
Publisher: Wiley
Binding: Hardcover
ISBN: 0471987875

Textbook of Clinical Trials

A comprehensive volume on clinical trials that covers all important disease and therapeutic areas together with methodologies, phase I/II/III studies and other issues. Medical books Textbook of Clinical Trials. br>
The volume catalogues the impact of clinical trials on the practice of medicine and discusses the developments and practice of medical statistics Medical books Textbook of Clinical Trials. Categories: Research design, Clinical trials. Contributors: David Machin - Editor. Format: Hardcover

Download link for Textbook of Clinical Trials

Categories: Research design, Clinical trials. Contributors: David Machin - Editor. Format: Hardcover

Categories: Clinical trials->Moral and ethical aspects, Human experimentation in medicine->Moral and ethical aspects, Medical ethics. Contributors: Ezekiel J. Emanuel - Author. Format: NOOK Book

Categories: Clinical trials->Moral and ethical aspects, Human experimentation in medicine->Moral and ethical aspects, Medical ethics. Contributors: Ezekiel J. Emanuel - Author. Format: Paperback

Categories: Clinical trials->Moral and ethical aspects, Human experimentation in medicine->Moral and ethical aspects, Medical ethics. Contributors: Ezekiel J. Emanuel - Author. Format: Paperback

Medical Book Textbook of Clinical Trials

br>
The volume catalogues the impact of clinical trials on the practice of medicine and discusses the developments and practice of medical statistics. Cancer, cardiovascular disease, dermatological, dental, mental, ophthalmic health, gynaecology and respiratory diseases are all discussed in separate chapters, with discussions on outcome measures, competing risks and statistical models given for each therapy area.


It also presents:
* A history of clinical trials
* A summary of pertinent statistical issues
* How to choose a clinical trial design
* Ethical constraints and considerations
* Clinical trial issues in paediatrics and those involving older patients
* Clinical trials in complementary medicine

A Concise Guide to Clinical Trials

Author: Allan Hackshaw
Edition: 1
Publisher: BMJ Books
Binding: Paperback
ISBN: 1405167742

A Concise Guide to Clinical Trials

Clinical trials have revolutionized the way disease is prevented, detected and treated, and early death avoided, and they continue to be an expanding area of research. Medical books A Concise Guide to Clinical Trials. They are central to the work of pharmaceutical companies, and there are many academic and public sector organizations that conduct trials on a wide variety of interventions, including drugs, devices, surgical techniques, and changes in behaviour and lifestyle.

A Concise Guide to Clinical Trials provides a comprehensive yet easy-to-read overview of the design, conduct and analysis of trials. It requires no prior knowledge on the subject as the important concepts are introduced throughout. There are chapters that distinguish between the different types of trials, and an introduction to systematic reviews, health-related quality of life and health economic evaluation Medical books A Concise Guide To Clinical Trials Ebook. Buy A Concise Guide to Clinical Trials by Allan Hackshaw and Read this Book on Kobo's Free Apps. Discover Kobo's Vast Collection of Ebooks Today - Over 3 Million Titles, Including 2 Million Free Ones!

Download link for A Concise Guide to Clinical Trials

Buy A Concise Guide to Clinical Trials by Allan Hackshaw and Read this Book on Kobo's Free Apps. Discover Kobo's Vast Collection of Ebooks Today - Over 3 Million Titles, Including 2 Million Free Ones!

A Concise Guide to Clinical Trials, ISBN-13: 9781405167741, ISBN-10: 1405167742

A Concise Guide to Clinical Trials

Store Search search Title, ISBN and Author A Concise Guide to Clinical Trials by Elizabeth Paul, Allan Hackshaw Estimated delivery 3-12 business days Format Paperback Condition Brand New Finally, a concise guide to setting up, conducting, and reporting a clinical trial. Covering the scientific basis of the design and analyses of clinical trials, including the statistical issues and how they are coordinated and regulated, this important paperback illuminates the path to success for the student o

Medical Book A Concise Guide to Clinical Trials

They are central to the work of pharmaceutical companies, and there are many academic and public sector organizations that conduct trials on a wide variety of interventions, including drugs, devices, surgical techniques, and changes in behaviour and lifestyle.

A Concise Guide to Clinical Trials provides a comprehensive yet easy-to-read overview of the design, conduct and analysis of trials. It requires no prior knowledge on the subject as the important concepts are introduced throughout. There are chapters that distinguish between the different types of trials, and an introduction to systematic reviews, health-related quality of life and health economic evaluation. The book also covers the ethical and legal requirements in setting up a clinical trial due to an increase in governance responsibilities and regulations.

This practical guidebook is ideal for busy clinicians and other health professionals who do not have enough time to attend courses or search through extensive textbooks. It will help anyone involved in undertaking clinical research, or those reading about trials. The book is aimed at:

• Those wishing to learn about clinical trials for the first time, or as a quick reference guide, for example as part of a taught course on clinical trials

• Health professionals who wish to conduct their own trials, or participate in other people’s studies
• People who work in pharmaceutical companies, grant funding organisations, or regulatory agencies

Design and Analysis of Cross-Over Trials, Second Edition

Author: Byron Jones
Edition: 2
Publisher: Chapman and Hall/CRC
Binding: Hardcover
ISBN: 0412606402

Design and Analysis of Cross-Over Trials, Second Edition (Chapman & Hall/CRC Monographs on Statistics & Applied Probability)

The first edition of Design and Analysis of Cross-Over Trials quickly became the standard reference on the subject and has remained so for more than 12 years. Medical books Design and Analysis of Cross-Over Trials, Second Edition . In that time, however, the use of cross-over trials has grown rapidly, particularly in the pharmaceutical arena, and researchers have made a number of advances in both the theory and methods applicable to these trials.

Completely revised and updated, the long-awaited second edition of this classic text retains its predecessor's careful balance of theory and practice while incorporating new approaches, more data sets, and a broader scope. Enhancements in the second edition include:

• A new chapter on bioequivalence
• Recently developed methods for analyzing longitudinal continuous and categorical data
• Real-world examples using the SAS system
• A comprehensive catalog of designs, datasets, and SAS programs available on a companion Web site at www.crcpress Medical books "Design and Analysis of Cross-Over Trials, Second Edition (Chapman & Hall/CRC Monographs on Statistics & Applied Probability)". "No description availableFile Size: 16654 KBPrint Length: 408 pagesPublisher: CRC Press; 1 edition (April 17, 2007) Sold by: Amazon Digital Services, Inc.Language: EnglishASIN: B000Q6GV4M"
  
  

  Download link for Design and Analysis of Cross-Over Trials, Second Edition (Chapman & Hall CRC Monographs on Statistics & Applied Probability)

  
  "No description availableFile Size: 16654 KBPrint Length: 408 pagesPublisher: CRC Press; 1 edition (April 17, 2007) Sold by: Amazon Digital Services, Inc.Language: EnglishASIN: B000Q6GV4M"
  
  
  
  "No description availableFile Size: 16654 KBPrint Length: 408 pagesPublisher: CRC Press; 1 edition (April 17, 2007) Sold by: Amazon Digital Services, Inc.Language: EnglishASIN: B000Q6GV4M"
  
  
  
  New Paperback.
  
  
  
  "No description availableFile Size: 16654 KBPrint Length: 408 pagesPublisher: CRC Press; 1 edition (April 17, 2007) Sold by: Amazon Digital Services, Inc.Language: EnglishASIN: B000Q6GV4M"
  
  
  
  
  

  Medical Book Design and Analysis of Cross-Over Trials, Second Edition

  
  
  In that time, however, the use of cross-over trials has grown rapidly, particularly in the pharmaceutical arena, and researchers have made a number of advances in both the theory and methods applicable to these trials.

  Completely revised and updated, the long-awaited second edition of this classic text retains its predecessor's careful balance of theory and practice while incorporating new approaches, more data sets, and a broader scope. Enhancements in the second edition include:

  • A new chapter on bioequivalence
  • Recently developed methods for analyzing longitudinal continuous and categorical data
  • Real-world examples using the SAS system
  • A comprehensive catalog of designs, datasets, and SAS programs available on a companion Web site at www.crcpress.com

  The authors' exposition gives a clear, unified account of the design and analysis of cross-over trials from a statistical perspective along with their methodological underpinnings. With SAS programs and a thorough treatment of design issues, Design and Analysis of Cross-Over Trials, Second Edition sets a new standard for texts in this area and undoubtedly will be of direct practical value for years to come.