Friday, November 18, 2011

Regulation of the Acute Phase and Immune Responses

Regulation of the Acute Phase and Immune Responses



Author: Pravinkumar B. Sehgal
Edition:
Publisher: New York Academy of Sciences
Binding: Hardcover
ISBN: 0897665317



Regulation of the Acute Phase and Immune Responses: Interleukin-6 (Annals of the New York Academy of Sciences)


Medical books Regulation of the Acute Phase and Immune Responses. Medical books Genetex - GTX100675 - C/EBP beta antibody, GeneTex (Each (100μl)). The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. [provided by RefSeq] This listing is for Each (100 l) Species Reactivity Human MW (kDa) 36 Host Rabbit Isotype IgG Unit Each (100 l) Application Note Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000 [suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)]. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. Immunogen Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 55 of C/EBP beta Monoclonal/Polyclonal Polyclonal Purification Purified by antigen-affinity chromatography. Storage Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Storage Instruction Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles. Tested Applications IHC-P, WB

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The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of

Cytokines are synthesized and secreted in the liver by Kupffer cells, and are important for inflammation processes, the non-specific immune response, and probably the destruction and removal of tumour cells. The production of signal substances such as tumour necrosis factor-alpha, interleukin 1 and 6, and interferon alpha/beta is regulated by a complex set of pathways, which can also be modified by cellular mediators, eg prostaglandins, growth factors and cortico-steroids. Signal exchange between different cell types in the liver is important for the synthesis of acute phase proteins, liver fi

Cytokines are synthesized and secreted in the liver by Kupffer cells, and are important for inflammation processes, the non-specific immune response, and probably the destruction and removal of tumour cells. Theproduction of signal substances such as tumour necrosis factor-alpha, interleukin 1 and 6, and interferon alpha/beta is regulated by a complex set of pathways, which can also be modified by cellular mediators, egprostaglandins, growth factors and cortico-steroids. Signal exchange between different cell types in the liver is important for the synthesis of acute phase proteins, liver fibr

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Medical Book Regulation of the Acute Phase and Immune Responses





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