Showing posts with label Cancer. Show all posts
Showing posts with label Cancer. Show all posts
Friday, December 19, 2014

Oxidative Stress in Cancer, AIDS, and Neurodegenerative Diseases

Oxidative Stress in Cancer, AIDS, and Neurodegenerative Diseases



Author: Luc Montagnier
Edition: 1st
Publisher: CRC Press
Binding: Hardcover
ISBN: 0824798627



Oxidative Stress in Cancer, AIDS, and Neurodegenerative Diseases (Oxidative Stress and Disease)


Based on a conference on Oxidative Stress and Redox Regulation, held at the Pasteur Institute, Paris, this work examines fundamental, chemical, biological and medical studies of free radicals on different targets and the consequences of their reactivity. Medical books Oxidative Stress in Cancer, AIDS, and Neurodegenerative Diseases . It covers the chemistry and biochemistry of free radicals, free radicals as second messengers that group the activation of transcription factors and enzymes, the importance of the antioxidant system in cell metabolism regulation, and the role of free radicals and antioxidants in disease management. The editors of this work are three of the most respected pioneers in the field. Dr. Montagnier is credited as the discoverer of HIV Medical books Oxidative Stress in Cancer, AIDS, and Neurodegenerative Diseases. Marcel Dekker | 1998 | 578 pages | ISBN-13: 9780824798628 | ISBN-10: 0824798627 | You save 15%

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Marcel Dekker | 1998 | 578 pages | ISBN-13: 9780824798628 | ISBN-10: 0824798627 | You save 15%

Categories: AIDS (Disease), Nervous system->Degeneration, Cancer->Pathophysiology. Contributors: Luc Montagnier - Author. Format: Hardcover

Presents basic chemical biological and medical studies of free radicals on different targets and the consequences of their reactivity covering the chemistry and biochemistry of free radicals free radicals as second messengers that group the activation of transcription factors and enzymes the importance of the antioxidant system in cell metabolism regulation and the role of free radicals and antioxidants in disease management Written by over 200 international authorities the book offers incisive discussions on the significance of oxidant antioxidant balance and cytotoxicity of free radicals whe

This book is written by Montagnier Published by CRC Press In 1998 and is available in Hardback POD will be shipped in 3 Days.



Medical Book Oxidative Stress in Cancer, AIDS, and Neurodegenerative Diseases



It covers the chemistry and biochemistry of free radicals, free radicals as second messengers that group the activation of transcription factors and enzymes, the importance of the antioxidant system in cell metabolism regulation, and the role of free radicals and antioxidants in disease management. The editors of this work are three of the most respected pioneers in the field. Dr. Montagnier is credited as the discoverer of HIV.

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Tuesday, November 18, 2014

Cancer Immunotherapy at the Crossroads

Cancer Immunotherapy at the Crossroads



Author:
Edition: 2004
Publisher: Humana Press
Binding: Hardcover
ISBN: 1588291839



Cancer Immunotherapy at the Crossroads: How Tumors Evade Immunity and What Can Be Done (Current Clinical Oncology)


Leading investigators and clinicians detail the different mechanisms used by tumors to escape and impair the immune system and then spell out possible clinical strategies to prevent or reverse tumor-induced immune dysfunction. Medical books Cancer Immunotherapy at the Crossroads. Medical books Vg, 1588291839, Cancer Immunotherapy At The Crossroads: How Tumors Evade Immunit. payment | shipping rates | returns Cancer Immunotherapy at the Crossroads: How Tumors Evade Immunity and What Can Be Done (Current Clinical Oncology) Product Category :Books ISBN :1588291839 Title :Cancer Immunotherapy at the Crossroads: How Tumors Evade Immunity and What Can Be Done (Current Clinical Oncology)EAN :9781588291837 Binding :Hardcover Publisher :Humana Press Publication Date :2003-11-24 Pages :408 Signed :False First Edition :False Dust Jacket :False List Price (MSRP) :199.00 Heigh

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payment | shipping rates | returns Cancer Immunotherapy at the Crossroads: How Tumors Evade Immunity and What Can Be Done (Current Clinical Oncology) Product Category :Books ISBN :1588291839 Title :Cancer Immunotherapy at the Crossroads: How Tumors Evade Immunity and What Can Be Done (Current Clinical Oncology)EAN :9781588291837 Binding :Hardcover Publisher :Humana Press Publication Date :2003-11-24 Pages :408 Signed :False First Edition :False Dust Jacket :False List Price (MSRP) :199.00 Heigh

Store Search search Title, ISBN and Author Cancer Immunotherapy at the Crossroads: How Tumors Evade Immunity and What Can Be Done by James H. Finke, Ronald M. Bukowski Estimated delivery 3-12 business days Format Hardcover Condition Brand New Leading investigators and clinicians detail the different mechanisms used by tumors to escape and impair the immune system and then spell out possible clinical strategies to prevent or reverse tumor-induced immune dysfunction. The authors review the mechan

Categories: Cancer->Immunological aspects, Neoplasms->Immunology, Cancer->Immunological aspects. Contributors: James H. Finke - Author. Format: Hardcover

This book is written by James H. Finke, Ronald M. Bukowski Published by Humana Press In 2004 and is available in Hardback Usually Ships in 3 Days.



Medical Book Cancer Immunotherapy at the Crossroads



The authors review the mechanisms of immune dysfunction and evasion mechanisms in histologically diverse human tumors, focusing on tumor-induced molecular defects in T cells and antigen-presenting cells (dendritic cells and tumors), that may serve as biomarkers for patient prognosis. They discuss the means by which these immune functions may be protected or restored in order to more effectively support the process of tumor rejection in situ. Cutting-edge techniques are outlined with the capacity to monitor the strength and quality of patients' immune responses using immunocytometry, MHC-peptide tetramers combined with apoptosis assay, ELISPOT assay, and detection of MHC-TAA peptide complexes on tumor cells.

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Sunday, October 5, 2014

Advances in Cancer Research, Volume 82 pdf

Advances in Cancer Research, Volume 82



Author:
Edition: 1
Publisher: Academic Press
Binding: Hardcover
ISBN: 0120066823



Advances in Cancer Research, Volume 82


Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Medical books Advances in Cancer Research, Volume 82. Medical books "Advances in Cancer Research, Volume 82". "Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics, including nitric oxide-induced apoptosis in tumor cells, detection of minimal residual disease, immunity to oncogenetic human papilloma viruses, and modeling prostate cancer in the mouse.File Size: 3528 KBPrint Length: 253 pagesPublisher: Academic Press; 1 edition (May 31, 2001) Sold by: Amazon Digital Services, Inc.Language: EnglishASIN: B000VRLHHC"

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"Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics, including nitric oxide-induced apoptosis in tumor cells, detection of minimal residual disease, immunity to oncogenetic human papilloma viruses, and modeling prostate cancer in the mouse.File Size: 3528 KBPrint Length: 253 pagesPublisher: Academic Press; 1 edition (May 31, 2001) Sold by: Amazon Digital Services, Inc.Language: EnglishASIN: B000VRLHHC"

"Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics, including nitric oxide-induced apoptosis in tumor cells, detection of minimal residual disease, immunity to oncogenetic human papilloma viruses, and modeling prostate cancer in the mouse.File Size: 3528 KBPrint Length: 253 pagesPublisher: Academic Press; 1 edition (May 31, 2001) Sold by: Amazon Digital Services, Inc.Language: EnglishASIN: B000VRLHHC"

"Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics, including nitric oxide-induced apoptosis in tumor cells, detection of minimal residual disease, immunity to oncogenetic human papilloma viruses, and modeling prostate cancer in the mouse.File Size: 3528 KBPrint Length: 253 pagesPublisher: Academic Press; 1 edition (May 31, 2001) Sold by: Amazon Digital Services, Inc.Language: EnglishASIN: B000VRLHHC"

"Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics, including nitric oxide-induced apoptosis in tumor cells, detection of minimal residual disease, immunity to oncogenetic human papilloma viruses, and modeling prostate cancer in the mouse.File Size: 3528 KBPrint Length: 253 pagesPublisher: Academic Press; 1 edition (May 31, 2001) Sold by: Amazon Digital Services, Inc.Language: EnglishASIN: B000VRLHHC"



Medical Book Advances in Cancer Research, Volume 82


  • ISBN13: 9780120066827
  • Condition: Used - Very Good
  • Notes: 100% Satisfaction Guarantee. Tracking provided on most orders. Buy with Confidence! Millions of books sold!

Here, once again, outstanding and original reviews are presented on a variety of topics, including nitric oxide-induced apoptosis in tumor cells, detection of minimal residual disease, immunity to oncogenetic human papilloma viruses, and modeling prostate cancer in the mouse.

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Thursday, May 29, 2014

DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology (Cancer

DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology (Cancer



Author: Vincent T DeVita
Edition: Eighth
Publisher: Lippincott Williams & Wilkins
Binding: Hardcover
ISBN: 0781772079



DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology (Cancer: Principles & Practice (DeVita)(2 Volume Set)


Acclaimed by the worldwide medical community as "a staple reference text in the medical oncologist's library" (JAMA), DeVita, Hellman, and Rosenberg's Cancer: Principles and Practice of Oncology is now in its Eighth Edition. Medical books DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology (Cancer. This edition is in full color for the first time, has a new editor, Theodore S. Lawrence, MD, PhD, a radiation oncologist, and has two Associate Scientific Advisors, Ronald A. DePinho, MD and Robert A. Weinberg, PhD, with special expertise in molecular biology Medical books Devita, Hellman, And Rosenberg's Cancer Principles & Practice Of Oncology Review. DeVita, Hellman, and Rosenberg's Cancer: Principles Practice of Oncology Review (Paperback, 2009) Books have never been used. Online access code has not been scratched off. Cover is slightly faded. Like Us On FaceBook! LCB Surplus LLC. Check out my other items ! Be sure to add me to your favorites list ! Powered by eBay Turbo Lister The free listing tool. List your items fast and easy and manage your active items. Additional Payment Information:Payment must be made within 4 days. Items ship wit

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DeVita, Hellman, and Rosenberg's Cancer: Principles Practice of Oncology Review (Paperback, 2009) Books have never been used. Online access code has not been scratched off. Cover is slightly faded. Like Us On FaceBook! LCB Surplus LLC. Check out my other items ! Be sure to add me to your favorites list ! Powered by eBay Turbo Lister The free listing tool. List your items fast and easy and manage your active items. Additional Payment Information:Payment must be made within 4 days. Items ship wit

Based on DeVita, Hellman, and Rosenberg's Cancer: Principles and Practice of Oncology, Seventh Edition, this comprehensive question-and-answer review book covers the entire specialty of oncology and provides thorough preparation for oncology boards. The book contains hundreds of multiple-choice and case-based questions covering the principles of surgical oncology, radiation oncology, medical oncology, and hematology/oncology and the biology, diagnosis, staging, and multimodality treatment of cancers at every anatomic site. Included are state-of-the-art chapters on molecular techniques, targete

Categories: Cancer, Oncology, Cancer. Contributors: Vincent T. DeVita Jr. - Editor. Format: Hardcover

Categories: Cancer, Oncology, Cancer. Contributors: Vincent T. DeVita Jr. - Editor. Format: Hardcover



Medical Book DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology (Cancer



This edition is in full color for the first time, has a new editor, Theodore S. Lawrence, MD, PhD, a radiation oncologist, and has two Associate Scientific Advisors, Ronald A. DePinho, MD and Robert A. Weinberg, PhD, with special expertise in molecular biology. More than 40 chapters are entirely new, and more than 70 have been rewritten by new contributing authors. Plus, this edition has an exciting new companion Website.

The text provides cutting-edge, practical information on the science of oncology and the multimodality treatment of every cancer type. To ensure a balanced, multidisciplinary approach, each major treatment chapter is co-authored by a surgeon, a medical oncologist, and a radiation oncologist. Treatment of each cancer type is discussed by stage, with coordinated guidelines on the role of each treatment modality at each stage. Each major treatment section is preceded by an updated brief chapter describing the molecular biology of the cancer and the implications of molecular biology for patient management. Full consideration is also given to cancer prevention, screening, palliative care, supportive oncology, and quality of life issues.

A companion Website offers the fully searchable online text, an image bank, links to journal articles, and a question bank.



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Thursday, September 6, 2012

The Psychoimmunology of Cancer pdf

The Psychoimmunology of Cancer



Author:
Edition: 2
Publisher: Oxford University Press, USA
Binding: Hardcover
ISBN: 0192630601



The Psychoimmunology of Cancer


When the first edition of this book published in 1994, the psychoimmunology of cancer was still emerging as a topic for serious scientific study. Medical books The Psychoimmunology of Cancer. Now, less than ten years later, there is a huge academic literature about the relationships between psychological variables, the immun system and cancer growth, accompanied by a lively popular interest.
In this new edition leading specialists have provided broad critical reviews of the different aspects.
Part I, which presents the biological background, will be of particular interest to those with technical knowledge of the relevant laboratory based disciplines. It covers mechanisms mediating the effects of psychological status in the immune system, and anti-cancer mechanisms involving the immune system Medical books The Psychoimmunology of Cancer. Categories: Cancer->Immunological aspects, Cancer->Psychological aspects->Popular works, Psychoneuroimmunology. Contributors: CE Lewis - Author. Format: Hardcover

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Categories: Cancer->Immunological aspects, Cancer->Psychological aspects->Popular works, Psychoneuroimmunology. Contributors: CE Lewis - Author. Format: Hardcover

Categories: Cancer->Immunological aspects, Cancer->Psychological aspects->Popular works, Psychoneuroimmunology. Contributors: CE Lewis - Author. Format: Hardcover

Categories: Cancer->Immunological aspects, Cancer->Psychological aspects->Popular works, Psychoneuroimmunology. Contributors: CE Lewis - Author. Format: Hardcover

The Psychoimmunology of Cancer (2nd Edition) by Lewis, CE/ O'Brien, RM/ Barraclough, J. [Hardcover]



Medical Book The Psychoimmunology of Cancer



Now, less than ten years later, there is a huge academic literature about the relationships between psychological variables, the immun system and cancer growth, accompanied by a lively popular interest.
In this new edition leading specialists have provided broad critical reviews of the different aspects.
Part I, which presents the biological background, will be of particular interest to those with technical knowledge of the relevant laboratory based disciplines. It covers mechanisms mediating the effects of psychological status in the immune system, and anti-cancer mechanisms involving the immune system. Part II is clinically oriented, and accessible to a wide audience. Whether psychotherapeutic interventions can help patients live longer, as well as coping better, is obviously the key question and several contributors considern the clinical evidence for this. A new speculative chapter on the spiritual context of immunity and cancer has also been added.
The psychoimmunology of cancer involves many complex issues, understanding of which remains far from complete. However, the contributors, besides reviewing the current state of knowledge and the implications for cancer patients, offer predictions for the future and ideas about furhter research.

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Monday, June 11, 2012

Introduction to the Cellular and Molecular Biology of Cancer

Introduction to the Cellular and Molecular Biology of Cancer



Author:
Edition: 4
Publisher: Oxford University Press, USA
Binding: Paperback
ISBN: 019852563X



Introduction to the Cellular and Molecular Biology of Cancer


This new edition o Introduction and Molecular Biology of Cancer provides a concise yet comprehensive overview of cancer biology, covering the current status of both research and treatment. Medical books Introduction to the Cellular and Molecular Biology of Cancer. For the student or new researcher the breadth of cancer research can appear daunting, yet a broad understanding is essential for translation of laboratory findings into the clinic.
Within the broad scope of the book, each topic is reviewed authoritatively by experts in the field, and the accompanying bibliographies allow rapid access to the relevant current literature. The book covers topics extending from the molecular alterations found in cancer cells and their causes to the current range of approaches to treatment. Since the publication of the previous edition in 1997 there has been unprecedented progress in cancer research: this is reflected by an extensive revision of all the material, and the addition of eight new chapters, covering DNA repair, epigenetic events, the cell cycle, cell immortalization, apoptosis, angiogenesis, animal models, the genome, transcriptome and proteome, radiotherapy and molecular radiotherapy, immunotherapy, and gene therapy Medical books Introduction To The Cellular And Molecular Biology Of Cancer By Knowles, Mar. Store Search search Title, ISBN and Author Introduction to the Cellular and Molecular Biology of Cancer by Knowles, Margaret Estimated delivery 3-12 business days Format Paperback Condition Brand New This new edition o Introduction and Molecular Biology of Cancer provides a concise yet comprehensive overview of cancer biology, covering the current status of both research and treatment. For the student or new researcher the breadth of cancer research can appear daunting, yet a broad understandin

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Store Search search Title, ISBN and Author Introduction to the Cellular and Molecular Biology of Cancer by Knowles, Margaret Estimated delivery 3-12 business days Format Paperback Condition Brand New This new edition o Introduction and Molecular Biology of Cancer provides a concise yet comprehensive overview of cancer biology, covering the current status of both research and treatment. For the student or new researcher the breadth of cancer research can appear daunting, yet a broad understandin

Introduction to the Cellular and Molecular Biology of Cancer

This new edition of "Introduction to the Cellular and Molecular Biology of Cancer" provides a comprehensive overview of cancer biology, covering the current status of both research and treatment. For the student or new researcher the breadth of cancer research can appear daunting, yet a broad understanding is essential for translation of laboratory findings into the clinic. Within the broad scope of the book, each topic is reviewed authoritatively by experts in the field, and the accompanying bibliographies allow rapid access to the relevant current literature. The book covers topics extending

This new edition of "Introduction to the Cellular and Molecular Biology of Cancer" provides a comprehensive overview of cancer biology, covering the current status of both research and treatment. For the student or new researcher the breadth of cancer research can appear daunting, yet a broad understanding is essential for translation of laboratory findings into the clinic. Within the broad scope of the book, each topic is reviewed authoritatively by experts in the field, and the accompanying bibliographies allow rapid access to the relevant current literature. The book covers topics extending



Medical Book Introduction to the Cellular and Molecular Biology of Cancer



For the student or new researcher the breadth of cancer research can appear daunting, yet a broad understanding is essential for translation of laboratory findings into the clinic.
Within the broad scope of the book, each topic is reviewed authoritatively by experts in the field, and the accompanying bibliographies allow rapid access to the relevant current literature. The book covers topics extending from the molecular alterations found in cancer cells and their causes to the current range of approaches to treatment. Since the publication of the previous edition in 1997 there has been unprecedented progress in cancer research: this is reflected by an extensive revision of all the material, and the addition of eight new chapters, covering DNA repair, epigenetic events, the cell cycle, cell immortalization, apoptosis, angiogenesis, animal models, the genome, transcriptome and proteome, radiotherapy and molecular radiotherapy, immunotherapy, and gene therapy. The fourth edition of the popular book will serve as a text for both undergraduate and postgraduate use and also as an introduction for clinicians and scientists new to the field.

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Thursday, May 17, 2012

Catching Cancer

Catching Cancer



Author: Claudia Cornwall
Edition: 1
Publisher: Rowman & Littlefield Publishers
Binding: Hardcover
ISBN: 1442215208



Catching Cancer: The Quest for its Viral and Bacterial Causes


Catching Cancer introduces readers to the investigators who created a medical revolution – a new way of looking at cancer and its causes. Medical books Catching Cancer. Featuring interviews with notable scientists such as Harald zur Hausen, Barry Marshall, Robin Warren, and others, the book tells the story of their struggles, their frustrations, and finally the breakthroughs that helped form some of the most profound changes in the way we view cancer. Claudia Cornwall takes readers inside the lab to reveal the long and winding path to discoveries that have changed and continue to alter the course of medical approaches to one of the most confounding diseases mankind has known. She tells the stories of families who have benefited from this new knowledge, of the researchers who made the revolution happen, and the breakthroughs that continue to change our lives. For years, we’ve thought cancer was the result of lifestyle choices, environmental factors, or genetic mutations Medical books Catching Cancer: The Quest For Its Viral And Bacterial Causes Ebook. The idea that you can catch cancer is radical, and yet several renowned scientists have shown that it is possible to do just that. Catching Cancer takes you inside a medical revolution and reveals the struggles of the scientists who persisted with their novel ideas despite opposition, disbelievers, and the challenges of expanding scientific frontiers in cancer research. Through interviews with the key players and an exploration of the science behind new discoveries, Claudia Cornwall reveals the key breakthroughs that set us on a course of better understanding how cancer develops and how we might prevent it.

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The idea that you can catch cancer is radical, and yet several renowned scientists have shown that it is possible to do just that. Catching Cancer takes you inside a medical revolution and reveals the struggles of the scientists who persisted with their novel ideas despite opposition, disbelievers, and the challenges of expanding scientific frontiers in cancer research. Through interviews with the key players and an exploration of the science behind new discoveries, Claudia Cornwall reveals the key breakthroughs that set us on a course of better understanding how cancer develops and how we mig

Categories: Health & Fitness - Diseases - Cancer * General. Contributors: Claudia Cornwall - Author. Format: Hardcover

Categories: Health & Fitness - Diseases - Cancer * General. Contributors: Claudia Cornwall - Author. Format: Hardcover

Categories: Health & Fitness - Diseases - Cancer * General. Contributors: Claudia Cornwall - Author. Format: Hardcover



Medical Book Catching Cancer



Featuring interviews with notable scientists such as Harald zur Hausen, Barry Marshall, Robin Warren, and others, the book tells the story of their struggles, their frustrations, and finally the breakthroughs that helped form some of the most profound changes in the way we view cancer. Claudia Cornwall takes readers inside the lab to reveal the long and winding path to discoveries that have changed and continue to alter the course of medical approaches to one of the most confounding diseases mankind has known. She tells the stories of families who have benefited from this new knowledge, of the researchers who made the revolution happen, and the breakthroughs that continue to change our lives. For years, we’ve thought cancer was the result of lifestyle choices, environmental factors, or genetic mutations. But pioneering scientists have begun to change that picture. We now know that infections cause 20 percent of cancers, including liver, stomach, and cervical cancer, which together kill almost 1.8 million people every year. While the idea that you can catch cancer may sound unsettling, it is actually good news. It means antibiotics and vaccines can be used to combat this most dreaded disease. With this understanding, we have new methods of preventing cancer, and perhaps we may be able to look forward to a day when we will no more fear cancer than we do polio or rubella.

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Tuesday, March 13, 2012

NF-kB, A Network Hub Controlling Immunity, Inflammation and Cancer

NF-kB, A Network Hub Controlling Immunity, Inflammation and Cancer



Author:
Edition: 1
Publisher: Cold Spring Harbor Laboratory
Binding: Paperback
ISBN: 1936113554



NF-kB, A Network Hub Controlling Immunity, Inflammation and Cancer


NF-kB is a critical signaling molecule in the immune system that regulates cell survival and cell death, lymphocyte responses, and inflammation. Medical books NF-kB, A Network Hub Controlling Immunity, Inflammation and Cancer. Acting as a transcription factor that can receive several inputs, it coordinates distinct gene expression programs in response to a wide variety of stimuli. Written and edited by experts in the field, this volume includes contributions covering the structure of NF-kB, its DNA-binding activity and specificity, the role of the inhibitor I-B, and canonical and alternative mechanisms of NF-kB activation. The contributors examine the physiological role of NF-kB in immune cells, as well as its functions in other tissues, such as the nervous system. They also discuss work indicating that NF-kB represents a critical link between inflammation and cancer Medical books Nf-Kb, a Network Hub Controlling Immunity, Inflammation, and Cancer.

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New Hardcover.

This vital reference covers the structure of the key cell signaling molecule NF-B, its DNA-binding activity and specificity, the role of the inhibitor I-B, canonical and alternative mechanisms of NDiscovering NF-kBDavid BaltimoreThe NF-kB Family of Transcription Factors and Its RegulationAndrea Oeckinghaus and Sankar GhoshSpecification of D



Medical Book NF-kB, A Network Hub Controlling Immunity, Inflammation and Cancer



Acting as a transcription factor that can receive several inputs, it coordinates distinct gene expression programs in response to a wide variety of stimuli. Written and edited by experts in the field, this volume includes contributions covering the structure of NF-kB, its DNA-binding activity and specificity, the role of the inhibitor I-B, and canonical and alternative mechanisms of NF-kB activation. The contributors examine the physiological role of NF-kB in immune cells, as well as its functions in other tissues, such as the nervous system. They also discuss work indicating that NF-kB represents a critical link between inflammation and cancer. Including clinical perspectives on the use of NF-kB inhibitors in cancer therapy and a historical introduction by David Baltimore, in whose lab NF-kB was discovered, this volume is a vital reference for cell and molecular biologists, immunologists, and pathologists interested in regulation of cell function.

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