Monday, July 11, 2011

Essentials of Medicinal Chemistry, 2nd Edition

Essentials of Medicinal Chemistry, 2nd Edition



Author: Andrejus Korolkovas
Edition: 2
Publisher: Wiley-Interscience
Binding: Hardcover
ISBN: 0471883565



Essentials of Medicinal Chemistry, 2nd Edition


This text/reference presents fundamental aspects of medicinal chemistry and contains comprehensive information on approximately 5,000 drugs currently in use, describing their therapeutic uses, their mechanisms of action, and their main side and harmful effects. Medical books Essentials of Medicinal Chemistry, 2nd Edition. Medical books Handbook of Drug Screening, Second Edition. Building upon the foundation of basics discussed in the previous edition, the Second Edition provides a more in-depth look at the latest methods and technologies of advanced drug screening, an essential function of drug discovery. With extensively updated content and 21 new chapters, this text examines: quality and efficiency of drug target validation and potential drug compound selection reducing assay costs and improvement in assay technology data quality improvement trends in drug discovery how drug screening can minimize adverse drug effects recent advancements, including: high content screening; protein-protein interactions; high-throughput crystallization; lead optimization; chemoinformatics and microfluidics technologies; target validation by genomics, proteomics, and siRNA; structure-based drug design; automation; and medicinal chemistry

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Building upon the foundation of basics discussed in the previous edition, the Second Edition provides a more in-depth look at the latest methods and technologies of advanced drug screening, an essential function of drug discovery. With extensively updated content and 21 new chapters, this text examines: quality and efficiency of drug target validation and potential drug compound selection reducing assay costs and improvement in assay technology data quality improvement trends in drug discovery how drug screening can minimize adverse drug effects recent advancements, including: high content scr

Jiro Tsuji, one of the pioneers in this field of organic synthesis, provides synthetic organic chemists with a remarkable overview of the many applications of organopalladium chemistry. Tsuji discusses the recent developments in the field as well as the explosive growth over the last five years. Highlighting the most recent discoveries in this rapidly expanding field, the book; Focuses on new aspects of organopalladium chemistry, putting emphasis on synthetic applications Investigates the new perspectives on the synthetic uses of contemporary organopalladium chemistry This volume, together wit

Kinetic studies of enzyme action provide powerful insights into the underlying mechanisms of catalysis and regulation These approaches are equally useful in examining the action of newly discovered enzymes and therapeutic agents Contemporary Enzyme Kinetics and Mechanism Second Edition presents key articles from Volumes 63 64 87 and 249 of Methods in Enzymology The chapters describe the most essential and widely applied strategies A set of exercises and problems is included to facilitate mastery of these topics The book will aid the reader to design execute and analyze kinetic experiments on e

This new edition provides an in-depth introduction to the theories and applications of the powder diffraction method for structure determination. The emphasis is placed on powder diffraction data collected using conventional x-ray sources, which remain primary tools for thousands of researchers and students in their daily experimental work. The book is divided into two parts: chapters one though fifteen give essential theoretical background, while chapters sixteen through twenty-five guide the reader through practical aspects of extracting structural information from powder data. Fundamentals



Medical Book Essentials of Medicinal Chemistry, 2nd Edition



Employs the latest World Health Organization (WHO) pharmacological classification and provides extensive information for drugs on WHO's latest list of basic or essential pharmaceuticals, including history: chemical, trade and generic names; chemical structure; obtention; physical and chemical properties; mechanisms of action; therapeutic uses; adverse reactions; biotransformation; chemical and pharmacological incompatibilities; bioavailability; dosage; storage; and assay.

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