Author:
Edition: Softcover reprint of hardcover 1st ed. 2007
Publisher: Springer
Binding: Paperback
ISBN: 1441924027
Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics (Biotechnology: Pharmaceutical Aspects)
Solvent systems are integral to drug development and pharmaceutical technology. Medical books Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics (Biotechnology. This single topic encompasses numerous allied subjects running the gamut from recrystallization solvents to biorelevant media. The goal of this contribution to the AAPS Biotechnology: Pharmaceutical Aspects series is to generate both a practical handbook as well as a reference allowing the reader to make effective decisions concerning the use of solvents and solvent systems. To this end, the monograph was created by inviting recognized experts from a number of fields to author relevant sections. Specifically, 15 chapters have been designed covering the theoretical background of solubility, the effect of ionic equilibria and pH on solubilization, the use of solvents to effect drug substance crystallization and polymorph selection, the use of solvent systems in high throughput screening and early discovery, solvent use in preformulation, the use of solvents in bio-relevant dissolution and permeation experiments, solvents and their use as toxicology vehicles, solubilizing media and excipients in oral and parenteral formulation development, specialized vehicles for protein formulation and solvent systems for topical and pulmonary drug administration Medical books Solvent Systems And Their Selection In Pharmaceutics And Biopharmaceutics (Biotechnology: Pharmaceutical Aspects) (Biotechnology: Pharmaceutical Aspects). New Hardcover.
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New Hardcover.
format hardback language english publication year 03 07 2007 series biotechnology pharmaceutical aspects subject engineering technology subject 2 industrial chemistry manufacturing title solvent systems and their selection in pharmaceutics and biopharmaceutics biotechnology pharmaceutical aspects biotechnology pharmaceutical aspects author augustijns patrick editor brewster marcus e editor publisher amer assn of pharmaceutical publication date apr 20 2007 pages 459 binding hardcover edition 1 st
Medical Book Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics (Biotechnology
This single topic encompasses numerous allied subjects running the gamut from recrystallization solvents to biorelevant media. The goal of this contribution to the AAPS Biotechnology: Pharmaceutical Aspects series is to generate both a practical handbook as well as a reference allowing the reader to make effective decisions concerning the use of solvents and solvent systems. To this end, the monograph was created by inviting recognized experts from a number of fields to author relevant sections. Specifically, 15 chapters have been designed covering the theoretical background of solubility, the effect of ionic equilibria and pH on solubilization, the use of solvents to effect drug substance crystallization and polymorph selection, the use of solvent systems in high throughput screening and early discovery, solvent use in preformulation, the use of solvents in bio-relevant dissolution and permeation experiments, solvents and their use as toxicology vehicles, solubilizing media and excipients in oral and parenteral formulation development, specialized vehicles for protein formulation and solvent systems for topical and pulmonary drug administration. The chapters are organized such that useful decision trees are included together with the scientific underpinning for their application. In addition, trends in the use of solvent systems and a balance of current views make this monograph useful to both the novice and experienced researcher and to scientists at all developmental stages from early discovery to late pharmaceutical operations.
